LOFT has partnered with Give Back Box to donate your gently used clothing and accessories to goodwill. To learn more, please read here and here. I'm always looking for those donation bins and now you can donate easily from the comfort of your home! There is no weight limit so I'll be looking for an extra large box. If you're having a hard time reselling your things then why not give it to someone in need? End the year on a good note.
Sell your items on eBay and donate a portion of your earnings to charity.
If you live in Massachusetts this not-for-profit organization's website lists other charitable organizations by (household goods) category.